Tom Sandbox

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 4: Line 4:
{{STRUCTURE_2zta| PDB=2zta | SCENE= }}
{{STRUCTURE_2zta| PDB=2zta | SCENE= }}
-
===DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX===
+
===GCN4 - Leucine Zipper===
- 
-
<!--
 
-
The line below this paragraph, {{ABSTRACT_PUBMED_1557122}}, adds the Publication Abstract to the page
 
-
(as it appears on PubMed at http://www.pubmed.gov), where 1557122 is the PubMed ID number.
 
-
-->
 
A specific DNA complex of the 65-residue, N-terminal fragment of the yeast transcriptional activator, GAL4, has been analysed at 2.7 A resolution by X-ray crystallography. The protein binds as a dimer to a symmetrical 17-base-pair sequence. A small, <scene name='Tom_Sandbox/Cd_binding/1'>Zn(2+)-containing domain </scene>recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. A short coiled-coil dimerization element imposes 2-fold symmetry. A segment of extended polypeptide chain links the metal-binding module to the dimerization element and specifies the length of the site. The relatively open structure of the complex would allow another protein to bind coordinately with GAL4.
A specific DNA complex of the 65-residue, N-terminal fragment of the yeast transcriptional activator, GAL4, has been analysed at 2.7 A resolution by X-ray crystallography. The protein binds as a dimer to a symmetrical 17-base-pair sequence. A small, <scene name='Tom_Sandbox/Cd_binding/1'>Zn(2+)-containing domain </scene>recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. A short coiled-coil dimerization element imposes 2-fold symmetry. A segment of extended polypeptide chain links the metal-binding module to the dimerization element and specifies the length of the site. The relatively open structure of the complex would allow another protein to bind coordinately with GAL4.
Line 16: Line 11:
==About this Structure==
==About this Structure==
-
[[1d66]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D66 OCA].
+
[[2zta]] is a 2 chain structure formed by
 +
 
==See Also==
==See Also==

Revision as of 00:25, 9 November 2011

Image:2zta.png


PDB ID 2zta

Drag the structure with the mouse to rotate
2zta, resolution 1.80Å ()
Non-Standard Residues:


Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Contents

GCN4 - Leucine Zipper

A specific DNA complex of the 65-residue, N-terminal fragment of the yeast transcriptional activator, GAL4, has been analysed at 2.7 A resolution by X-ray crystallography. The protein binds as a dimer to a symmetrical 17-base-pair sequence. A small, recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. A short coiled-coil dimerization element imposes 2-fold symmetry. A segment of extended polypeptide chain links the metal-binding module to the dimerization element and specifies the length of the site. The relatively open structure of the complex would allow another protein to bind coordinately with GAL4.


PDB ID 1ysa

Drag the structure with the mouse to rotate
1ysa, resolution 2.90Å ()
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



About this Structure

2zta is a 2 chain structure formed by


See Also

Reference

Proteopedia Page Contributors and Editors (what is this?)

Alan Tom

Retrieved from "http://52.214.119.220/wiki/index.php/Tom_Sandbox"
Personal tools