Tom Sandbox

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===GCN4 - Leucine Zipper===
===GCN4 - Leucine Zipper===
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A specific DNA complex of the 65-residue, N-terminal fragment of the yeast transcriptional activator, GAL4, has been analysed at 2.7 A resolution by X-ray crystallography. The protein binds as a dimer to a symmetrical 17-base-pair sequence. A small, <scene name='Tom_Sandbox/Cd_binding/1'>Zn(2+)-containing domain </scene>recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. A short coiled-coil dimerization element imposes 2-fold symmetry. A segment of extended polypeptide chain links the metal-binding module to the dimerization element and specifies the length of the site. The relatively open structure of the complex would allow another protein to bind coordinately with GAL4.
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Blah blah information about leucine zipper GCN4.
{{STRUCTURE_1ysa| PDB=1ysa | SCENE= }}
{{STRUCTURE_1ysa| PDB=1ysa | SCENE= }}
==About this Structure==
==About this Structure==
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[[2zta]] is a 2 chain structure formed by
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[[2zta]] is composed of two identical 52 residue alpha helix chains that grouped together to form a dimer. The dimer binds through interlocking leucine amino acids in the C terminal ends, while pinching in on the major groove of DNA in the N terminal end.
==See Also==
==See Also==
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*[[Hydrogen in macromolecular models]]
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[[2zta]]
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[[1ysa]]
==Reference==
==Reference==
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<ref group="xtra">PMID:1557122</ref><references group="xtra"/>
 
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[[Category: Saccharomyces cerevisiae]]
 
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[[Category: Carey, M.]]
 
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[[Category: Harrison, S C.]]
 
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[[Category: Marmorstein, R.]]
 
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[[Category: Ptashne, M.]]
 
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[[Category: Double helix]]
 
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[[Category: Protein-dna complex]]
 
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[[Category: Transcription/dna complex]]
 

Revision as of 00:34, 9 November 2011

Image:2zta.png


PDB ID 2zta

Drag the structure with the mouse to rotate
2zta, resolution 1.80Å ()
Non-Standard Residues:


Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Contents

GCN4 - Leucine Zipper

Blah blah information about leucine zipper GCN4.


PDB ID 1ysa

Drag the structure with the mouse to rotate
1ysa, resolution 2.90Å ()
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



About this Structure

2zta is composed of two identical 52 residue alpha helix chains that grouped together to form a dimer. The dimer binds through interlocking leucine amino acids in the C terminal ends, while pinching in on the major groove of DNA in the N terminal end.


See Also

2zta 1ysa

Reference

Proteopedia Page Contributors and Editors (what is this?)

Alan Tom

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