1v0n
From Proteopedia
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| - | [[Image:1v0n.jpg|left|200px]]<br /><applet load="1v0n" size=" | + | [[Image:1v0n.jpg|left|200px]]<br /><applet load="1v0n" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1v0n, resolution 1.10Å" /> | caption="1v0n, resolution 1.10Å" /> | ||
'''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5'''<br /> | '''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1V0N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans] with EDO and IMD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] Known structural/functional Site: <scene name='pdbsite=AC1:Catalytic Nucleophile'>AC1</scene>. Full crystallographic information is available from [http:// | + | 1V0N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans] with <scene name='pdbligand=EDO:'>EDO</scene> and <scene name='pdbligand=IMD:'>IMD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] Known structural/functional Site: <scene name='pdbsite=AC1:Catalytic+Nucleophile'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V0N OCA]. |
==Reference== | ==Reference== | ||
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[[Category: xylanase]] | [[Category: xylanase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:13:24 2008'' |
Revision as of 08:13, 3 February 2008
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XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5
Overview
The atomic resolution structures of xylobiose-derived isofagomine and, xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A, from Streptomyces lividans reveal undistorted (4)C(1) chair conformed, sugars and, in the case of the deoxynojirimycin analogue, suggest unusual, pK(a) changes of the enzyme's catalytic machinery upon binding.
About this Structure
1V0N is a Single protein structure of sequence from Streptomyces lividans with and as ligands. Active as Endo-1,4-beta-xylanase, with EC number 3.2.1.8 Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A., Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ, Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887
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