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3qd0

From Proteopedia

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==Reference==
==Reference==
-
<ref group="xtra">PMID:21341675</ref><references group="xtra"/>
+
<ref group="xtra">PMID:021341675</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Ward, P.]]
[[Category: Ward, P.]]
[[Category: Xiang, H.]]
[[Category: Xiang, H.]]
 +
[[Category: Agc kinase]]
 +
[[Category: Kinase domain]]
 +
[[Category: Phosphoinositide]]
 +
[[Category: Phosphorylation on s241]]
 +
[[Category: Signal transduction]]
 +
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 10:40, 16 November 2011

Template:STRUCTURE 3qd0

Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with (2R,5S)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-6-methyl-N-phenyl-3-piperidinecarboxamide

Template:ABSTRACT PUBMED 21341675

About this Structure

3qd0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Medina JR, Becker CJ, Blackledge CW, Duquenne C, Feng Y, Grant SW, Heerding D, Li WH, Miller WH, Romeril SP, Scherzer D, Shu A, Bobko MA, Chadderton AR, Dumble M, Gardiner CM, Gilbert S, Liu Q, Rabindran SK, Sudakin V, Xiang H, Brady PG, Campobasso N, Ward P, Axten JM. Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors. J Med Chem. 2011 Feb 22. PMID:21341675 doi:10.1021/jm101527u

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OCA

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