Mannosidase
From Proteopedia
| Line 6: | Line 6: | ||
==3D structures of mannosidase== | ==3D structures of mannosidase== | ||
| + | |||
| + | ''Updated December 2011'' | ||
===α-MAN=== | ===α-MAN=== | ||
[[1hcu]] - αMAN – ''Trichoderma reesei''<br /> | [[1hcu]] - αMAN – ''Trichoderma reesei''<br /> | ||
| - | [[1o7d]] - αMAN – bovine | + | [[1o7d]] - αMAN – bovine<br /> |
| + | [[2wvy]], [[2ww2]] - αMAN - ''Bacterioides thetaiotaomicron'' | ||
===α-MAN class I=== | ===α-MAN class I=== | ||
| Line 20: | Line 23: | ||
[[2ri8]] - PcαMAN I + glycerol – ''Penicillium citrinum''<br /> | [[2ri8]] - PcαMAN I + glycerol – ''Penicillium citrinum''<br /> | ||
[[1kre]], [[1kkt]] - PcαMAN I + mannose<br /> | [[1kre]], [[1kkt]] - PcαMAN I + mannose<br /> | ||
| + | [[2ri9]] - PcαMAN I + substrate analog<br /> | ||
[[1krf]] - PcαMAN I + kifunensine + mannose<br /> | [[1krf]] - PcαMAN I + kifunensine + mannose<br /> | ||
[[1x9d]] - hαMAN I residues 243-699 + polysaccharide analog<br /> | [[1x9d]] - hαMAN I residues 243-699 + polysaccharide analog<br /> | ||
| Line 55: | Line 59: | ||
===β-MAN=== | ===β-MAN=== | ||
| - | [[2je8]] - BtβMAN residues 26-864 | + | [[2je8]] - BtβMAN residues 26-864 <br /> |
[[2wbk]] - BtβMAN residues 26-864 + mannopyranoside <br /> | [[2wbk]] - BtβMAN residues 26-864 + mannopyranoside <br /> | ||
[[2vqt]], [[2vr4]], [[2vjx]], [[2vl4]], [[2vmf]], [[2vo5]], [[2vot]], [[2vqu]] - BtβMAN residues 26-864 + piperidine derivative<br /> | [[2vqt]], [[2vr4]], [[2vjx]], [[2vl4]], [[2vmf]], [[2vo5]], [[2vot]], [[2vqu]] - BtβMAN residues 26-864 + piperidine derivative<br /> | ||
[[1oh4]], [[1of4]] - TmβMAN catalytic domain + mannose – ''Thermotoga maritima''<br /> | [[1oh4]], [[1of4]] - TmβMAN catalytic domain + mannose – ''Thermotoga maritima''<br /> | ||
[[1of3]] - TmβMAN catalytic domain<br /> | [[1of3]] - TmβMAN catalytic domain<br /> | ||
| + | [[1gvy]] - βMAN (mutant) + mannotrioside – ''Pseudomonas cellulose''<br /> | ||
| + | [[1uz4]] - CmβMAN + inhibitor – ''Cellvibrio mixtus''<br /> | ||
| + | [[1uuq]] - CmβMAN<br /> | ||
| + | [[2c0h]] - βMAN (mutant) – blue mussel<br /> | ||
| + | [[2whk]] - βMAN – ''Bacillus subtilis'' | ||
Revision as of 11:15, 4 December 2011
Mannosidase (MAN) is an enzyme which hydrolyzes mannose. There are 2 kinds of MAN. αMAN which hydrolyzes α-mannose and βMAN. See some details in Molecular Playground/ERMan1.
3D structures of mannosidase
Updated December 2011
α-MAN
1hcu - αMAN – Trichoderma reesei
1o7d - αMAN – bovine
2wvy, 2ww2 - αMAN - Bacterioides thetaiotaomicron
α-MAN class I
1fmi - hαMAN I - human
1fo2 - hαMAN I + deoxymannojirimycin
1fo3 - hαMAN I+ kifunensine
1dl2 - αMAN I catalytic domain + mannose - yeast
2ri8 - PcαMAN I + glycerol – Penicillium citrinum
1kre, 1kkt - PcαMAN I + mannose
2ri9 - PcαMAN I + substrate analog
1krf - PcαMAN I + kifunensine + mannose
1x9d - hαMAN I residues 243-699 + polysaccharide analog
1nxc - αMAN I + mannose – mouse
1g6i - αMAN I + deoxymannojirimycin
α-MAN class II
2wyh - SpαMAN II – Streptococcus pyrogenes
3bub, 1hty - DmαMAN II catalytic domain – Drosophila melanogaster
3bud - DmαMAN II catalytic domain (mutant)
3bui - DmαMAN II catalytic domain (mutant) + Tris
3bup, 3buq, 3czs - DmαMAN II catalytic domain (mutant) + mannose
3bvt, 3bvu, 3bvv, 3bvw, 3bvx - DmαMAN II catalytic domain (mutant) + mannopyranoside
1r33, 1r34 - DmαMAN II catalytic domain + mannopyranoside
3ddf, 3ddg, 2f18, 2f1a, 2f1b - DmαMAN II catalytic domain + pyrrolidin
2alw - DmαMAN II catalytic domain + noeuromycin
3cv5 - DmαMAN II catalytic domain + polysaccharide
3czn - DmαMAN II catalytic domain (mutant) + polysaccharide
2wyi - SpαMAN II + swainsonine
3blb, 1hww - DmαMAN II + swainsonine
3ejp, 3ejq, 3ejr, 3ejs, 3ejt, 3eju, 2ow6, 2ow7 - DmαMAN II catalytic domain + swainsonine analog
3dx0, 3dx2, 2f7o - DmαMAN II catalytic domain + mannostatine
3dx1, 3dx3, 3dx4, 2f7p - DmαMAN II catalytic domain + mannostatine analog
3d4y, 3d4z - DmαMAN II catalytic domain + imidazole derivative
3d50, 3d51, 3d52 - DmαMAN II catalytic domain + inhibitor
2fyv, 2f7q, 2f7r - DmαMAN II catalytic domain + amino-salacinol carboxylate analog
1tqv, 1tqw, 1tqs, 1tqt, 1tqu - DmαMAN II catalytic domain (mutant) + seleno-salacinol
1ps3 - DmαMAN II catalytic domain + kifunensine
1qwn - DmαMAN II catalytic domain + intermediate
1hxk - DmαMAN II catalytic domain + deoxymannojirimycin
1qwu - DmαMAN II catalytic domain (mutant) + guloside
1qx1 - DmαMAN II catalytic domain (mutant) + mannosyl
β-MAN
2je8 - BtβMAN residues 26-864
2wbk - BtβMAN residues 26-864 + mannopyranoside
2vqt, 2vr4, 2vjx, 2vl4, 2vmf, 2vo5, 2vot, 2vqu - BtβMAN residues 26-864 + piperidine derivative
1oh4, 1of4 - TmβMAN catalytic domain + mannose – Thermotoga maritima
1of3 - TmβMAN catalytic domain
1gvy - βMAN (mutant) + mannotrioside – Pseudomonas cellulose
1uz4 - CmβMAN + inhibitor – Cellvibrio mixtus
1uuq - CmβMAN
2c0h - βMAN (mutant) – blue mussel
2whk - βMAN – Bacillus subtilis
