Gramicidin
From Proteopedia
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[[Image:2xdc.png|left|200px|thumb|Crystal Structure of Gramicidin, [[2xdc]]]] | [[Image:2xdc.png|left|200px|thumb|Crystal Structure of Gramicidin, [[2xdc]]]] | ||
| - | <Structure load='2xdc' size=' | + | <Structure load='2xdc' size='400' scene='Gramicidin/Cv/1' frame='true' align='right' caption='Gramicidin D, [[2xdc]]'/> |
[[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. | [[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. | ||
| - | GCDN S is an antibiotic | + | GCDN S is an antibiotic. See theoretical model of [[Gramicidin Channel in Lipid Bilayer]]. |
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
Revision as of 15:38, 12 January 2012
Image:2xdc.png
Crystal Structure of Gramicidin, 2xdc
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Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. GCDN S is an antibiotic. See theoretical model of Gramicidin Channel in Lipid Bilayer.
3D Structures of Gramicidin
Update November 2011
Gramicidin A
1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
1tkq - GCDN A + mini-GCDN A – NMR
1av2 - GCDN A + CsCl
1gmk - GCDN A + KCNS
Gramicidin D
2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D
3lml, 2izq, 3i8i, 3l8l - GCDN D + iodide
1c4d - GCDN D + CsCl
Gramicidin S
1tk2 – GCDN S + subtilisin savinase – Bacillus lentus
