1oah
From Proteopedia
(New page: 200px<br /> <applet load="1oah" size="450" color="white" frame="true" align="right" spinBox="true" caption="1oah, resolution 2.3Å" /> '''CYTOCHROME C NITRITE...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1OAH is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]] with CA, CL, ZN and HEM as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.2.2 1.7.2.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OAH OCA]]. | + | 1OAH is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]] with CA, CL, ZN and HEM as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Nitrite_reductase_(cytochrome;_ammonia-forming) Nitrite reductase (cytochrome; ammonia-forming)]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.2.2 1.7.2.2]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OAH OCA]]. |
==Reference== | ==Reference== | ||
Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA)., Cunha CA, Macieira S, Dias JM, Almeida G, Goncalves LL, Costa C, Lampreia J, Huber R, Moura JJ, Moura I, Romao MJ, J Biol Chem. 2003 May 9;278(19):17455-65. Epub 2003 Mar 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12618432 12618432] | Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA)., Cunha CA, Macieira S, Dias JM, Almeida G, Goncalves LL, Costa C, Lampreia J, Huber R, Moura JJ, Moura I, Romao MJ, J Biol Chem. 2003 May 9;278(19):17455-65. Epub 2003 Mar 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12618432 12618432] | ||
[[Category: Desulfovibrio desulfuricans]] | [[Category: Desulfovibrio desulfuricans]] | ||
| + | [[Category: Nitrite reductase (cytochrome; ammonia-forming)]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Almeida, G.]] | [[Category: Almeida, G.]] | ||
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[[Category: respiratory nitrite ammonification]] | [[Category: respiratory nitrite ammonification]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:54:37 2007'' |
Revision as of 10:49, 30 October 2007
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CYTOCHROME C NITRITE REDUCTASE FROM DESULFOVIBRIO DESULFURICANS ATCC 27774: THE RELEVANCE OF THE TWO CALCIUM SITES IN THE STRUCTURE OF THE CATALYTIC SUBUNIT (NRFA).
Overview
The gene encoding cytochrome c nitrite reductase (NrfA) from Desulfovibrio, desulfuricans ATCC 27774 was sequenced and the crystal structure of the, enzyme was determined to 2.3-A resolution. In comparison with homologous, structures, it presents structural differences mainly located at the, regions surrounding the putative substrate inlet and product outlet, and, includes a well defined second calcium site with octahedral geometry, coordinated to propionates of hemes 3 and 4, and caged by a loop, non-existent in the previous structures. The highly negative electrostatic, potential in the environment around hemes 3 and 4 suggests that the main, role of this calcium ion may not be electrostatic but structural, namely, in the stabilization of the conformation of the additional loop that ... [(full description)]
About this Structure
1OAH is a [Single protein] structure of sequence from [Desulfovibrio desulfuricans] with CA, CL, ZN and HEM as [ligands]. Active as [Nitrite reductase (cytochrome; ammonia-forming)], with EC number [1.7.2.2]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA)., Cunha CA, Macieira S, Dias JM, Almeida G, Goncalves LL, Costa C, Lampreia J, Huber R, Moura JJ, Moura I, Romao MJ, J Biol Chem. 2003 May 9;278(19):17455-65. Epub 2003 Mar 4. PMID:12618432
Page seeded by OCA on Tue Oct 30 12:54:37 2007
Categories: Desulfovibrio desulfuricans | Nitrite reductase (cytochrome; ammonia-forming) | Single protein | Almeida, G. | Costa, C. | Cunha, C.A. | Dias, J.M. | Goncalves, L.L. | Huber, R. | Lampreia, J. | Macieira, S. | Moura, I. | Moura, J.J.G. | Romao, M.J. | CA | CL | HEM | ZN | Cytochrome c | Nitrite reductase | Nitrogen cycle | Respiratory nitrite ammonification
