1oa7
From Proteopedia
(New page: 200px<br /> <applet load="1oa7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1oa7, resolution 2.0Å" /> '''STRUCTURE OF MELANOC...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1OA7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]] with CBI as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OA7 OCA]]. | + | 1OA7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]] with CBI as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Cellulase Cellulase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OA7 OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of a family 45 endoglucanase from Melanocarpus albomyces: mechanistic implications based on the free and cellobiose-bound forms., Hirvonen M, Papageorgiou AC, J Mol Biol. 2003 Jun 6;329(3):403-10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12767825 12767825] | Crystal structure of a family 45 endoglucanase from Melanocarpus albomyces: mechanistic implications based on the free and cellobiose-bound forms., Hirvonen M, Papageorgiou AC, J Mol Biol. 2003 Jun 6;329(3):403-10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12767825 12767825] | ||
| + | [[Category: Cellulase]] | ||
[[Category: Melanocarpus albomyces]] | [[Category: Melanocarpus albomyces]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 21: | Line 22: | ||
[[Category: glycoside hydrolases]] | [[Category: glycoside hydrolases]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:54:40 2007'' |
Revision as of 10:49, 30 October 2007
|
STRUCTURE OF MELANOCARPUS ALBOMYCES ENDOGLUCANASE IN COMPLEX WITH CELLOBIOSE
Overview
Cellulose, a polysaccharide of beta-1,4-linked D-glucosyl units, is the, major component of plant cell walls and one of the most abundant, biopolymers in nature. Cellulases (cellobiohydrolases and endoglucanases), are enzymes that catalyse the hydrolysis of cellulose to smaller, oligosaccharides, a process of paramount importance in biotechnology. The, thermophilic fungus Melanocarpus albomyces produces a 20 kDa endoglucanase, known as 20K-cellulase that has been found particularly useful in the, textile industry. The crystal structures of free 20K-cellulase and its, complex with cellobiose have been determined at 2.0 A resolution. The, enzyme, classified into the glycoside hydrolase family 45, exhibits the, characteristic six-stranded beta-barrel found before in Humicola insolens, ... [(full description)]
About this Structure
1OA7 is a [Single protein] structure of sequence from [Melanocarpus albomyces] with CBI as [ligand]. Active as [Cellulase], with EC number [3.2.1.4]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of a family 45 endoglucanase from Melanocarpus albomyces: mechanistic implications based on the free and cellobiose-bound forms., Hirvonen M, Papageorgiou AC, J Mol Biol. 2003 Jun 6;329(3):403-10. PMID:12767825
Page seeded by OCA on Tue Oct 30 12:54:40 2007
