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1bqy
From Proteopedia
(New page: 200px<br /> <applet load="1bqy" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bqy, resolution 2.50Å" /> '''PLASMINOGEN ACTIVAT...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1BQY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | + | 1BQY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Viridovipera_stejnegeri Viridovipera stejnegeri]]. Structure known Active Site: . Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BQY OCA]]. |
==Reference== | ==Reference== | ||
The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases., Parry MA, Jacob U, Huber R, Wisner A, Bon C, Bode W, Structure. 1998 Sep 15;6(9):1195-206. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9753698 9753698] | The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases., Parry MA, Jacob U, Huber R, Wisner A, Bon C, Bode W, Structure. 1998 Sep 15;6(9):1195-206. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9753698 9753698] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: | + | [[Category: Viridovipera stejnegeri]] |
[[Category: Bode, W.]] | [[Category: Bode, W.]] | ||
[[Category: Parry, M.A.A.]] | [[Category: Parry, M.A.A.]] | ||
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[[Category: snake venom]] | [[Category: snake venom]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:58:36 2007'' |
Revision as of 10:53, 30 October 2007
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PLASMINOGEN ACTIVATOR (TSV-PA) FROM SNAKE VENOM
Overview
BACKGROUND: Trimeresurus stejnejeri venom plasminogen activator (TSV-PA), is a snake venom serine proteinase that specifically activates, plasminogen. Snake venom serine proteinases form a subfamily of, trypsin-like proteinases that are characterised by a high substrate, specificity and resistance to inhibition. Many of these venom enzymes, specifically interfere with haemostatic mechanisms and display a long, circulating half-life. For these reasons several of them have commercial, applications and are potentially attractive pharmacological tools., RESULTS: The crystal structure of TSV-PA has been determined to 2.5 A, resolution and refined to an R factor of 17.8 (R free, 24.4). The enzyme, showing the overall polypeptide fold of trypsin-like serine proteinases, displays unique ... [(full description)]
About this Structure
1BQY is a [Single protein] structure of sequence from [Viridovipera stejnegeri]. Structure known Active Site: . Full crystallographic information is available from [OCA].
Reference
The crystal structure of the novel snake venom plasminogen activator TSV-PA: a prototype structure for snake venom serine proteinases., Parry MA, Jacob U, Huber R, Wisner A, Bon C, Bode W, Structure. 1998 Sep 15;6(9):1195-206. PMID:9753698
Page seeded by OCA on Tue Oct 30 12:58:36 2007
