2jhc
From Proteopedia
(New page: 200px<br /> <applet load="2jhc" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jhc, resolution 3.00Å" /> '''THE STRUCTURE OF BL...) |
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==About this Structure== | ==About this Structure== | ||
- | 2JHC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)]] with GUN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA]]. | + | 2JHC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)]] with GUN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: virion protein]] | [[Category: virion protein]] | ||
- | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:06:28 2007'' |
Revision as of 11:01, 30 October 2007
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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
Overview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series, of four chemical reactions. Some viruses achieve this using a single, molecule; the crystal structure of such an enzyme from bluetongue virus, reveals an elongated modular architecture that provides a scaffold for an, assemblage of active sites, two contributed by a domain of novel, structure.
About this Structure
2JHC is a [Single protein] structure of sequence from [Bluetongue virus 10 (isolate usa)] with GUN as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
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