4ajp
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:4ajp. | + | [[Image:4ajp.png|left|200px]] |
<!-- | <!-- | ||
| Line 11: | Line 11: | ||
===Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid=== | ===Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22417091}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22417091 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_22417091}} | ||
==About this Structure== | ==About this Structure== | ||
[[4ajp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJP OCA]. | [[4ajp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJP OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022417091</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: L-lactate dehydrogenase]] | [[Category: L-lactate dehydrogenase]] | ||
Revision as of 08:06, 25 April 2012
Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid
Template:ABSTRACT PUBMED 22417091
About this Structure
4ajp is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ward RA, Brassington C, Breeze AL, Caputo A, Critchlow S, Davies G, Goodwin L, Hassall G, Greenwood R, Holdgate GA, Mrosek M, Norman RA, Pearson S, Tart J, Tucker JA, Vogtherr M, Whittaker D, Wingfield J, Winter J, Hudson K. Design and synthesis of novel lactate dehydrogenase a inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306. Epub 2012 Mar 26. PMID:22417091 doi:10.1021/jm201734r
