1uxc
From Proteopedia
(New page: 200px<br /> <applet load="1uxc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1uxc" /> '''FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR,...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1UXC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UXC OCA]]. | + | 1UXC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Structure known Active Site: HTH. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UXC OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:14:43 2007'' |
Revision as of 11:10, 30 October 2007
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FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE
Overview
FruR is an Escherichia coli transcriptional regulator that belongs to the, LacI DNA-binding protein family. By using 1H and 15N NMR spectroscopy, we, have determined the three-dimensional solution structure of the FruR, N-terminal DNA-binding domain consisting of 57 amino acid residues. A, total of 809 NMR-derived distances and 54 dihedral angle constraints have, been used for molecular modelling with the X-PLOR program. The resulting, set of calculated structures presents an average root-mean-square, deviation of 0.37 A at the main-chain level for the first 47 residues., This highly defined N-terminal part of the structure reveals a similar, topology for the three alpha-helices when compared to the 3D structures of, LacI and PurR counterparts. The most striking difference lies in the, ... [(full description)]
About this Structure
1UXC is a [Single protein] structure of sequence from [Escherichia coli]. Structure known Active Site: HTH. Full crystallographic information is available from [OCA].
Reference
Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR., Penin F, Geourjon C, Montserret R, Bockmann A, Lesage A, Yang YS, Bonod-Bidaud C, Cortay JC, Negre D, Cozzone AJ, Deleage G, J Mol Biol. 1997 Jul 18;270(3):496-510. PMID:9237914
Page seeded by OCA on Tue Oct 30 13:14:43 2007
