Pre-mRNA-splicing factor

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== 3D Structures of pre-mRNA splicing factors ==
== 3D Structures of pre-mRNA splicing factors ==
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''Update June 2012''
===Pre-mRNA-splicing factor 2===
===Pre-mRNA-splicing factor 2===
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[[3e66]] – yPrp β-finger domain<BR />
[[3e66]] – yPrp β-finger domain<BR />
[[3e9o]], [[3e9p]] - yPrp RNA-binding domain<BR />
[[3e9o]], [[3e9p]] - yPrp RNA-binding domain<BR />
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[[2p87]], [[2og4]] - yPrp C terminal<BR />
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[[2p87]], [[2og4]], [[3sbg]] - yPrp C terminal<BR />
[[3lru]] – hPrp residues 1831-1990<BR />
[[3lru]] – hPrp residues 1831-1990<BR />
[[3e9l]] – hPrp endonuclease domain<BR />
[[3e9l]] – hPrp endonuclease domain<BR />
[[3enb]] - hPrp core domain IV<BR />
[[3enb]] - hPrp core domain IV<BR />
[[2p8r]] – Prp C terminal (mutant) – ''Caenorhabditis elegans''
[[2p8r]] – Prp C terminal (mutant) – ''Caenorhabditis elegans''
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===Pre-mRNA-splicing factor 9===
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[[4dgw]] – yPrp + Prp 21 + Prp 11
===Pre-mRNA-splicing factor 18===
===Pre-mRNA-splicing factor 18===

Revision as of 10:45, 21 June 2012

Template:STRUCTURE 3e9l

Pre-mRNA-splicing factors (Prp) are the proteins which associate with mRNA at its various splicing sites to produce alternative splicing. For details on pre-mRNA-splicing factors and Prp24 see Prp24; see detailed Prp19.

3D Structures of pre-mRNA splicing factors

Update June 2012

Pre-mRNA-splicing factor 2

3beg – hPrp residues 105-219 + Ser/Thr-protein kinase – human
2o3d – hPrp P33 subunit

Pre-mRNA-splicing factor 3

1x4q – hPrp PWI domain - NMR

Pre-mRNA-splicing factor 3B

3lqv, 2f9d, 2f9j – hPrp residues 377-415 + pre-mRNA branch site protein 14
2fho - hPrp residues 379-424 + spliceosomal protein P14 - NMR
2do5 – hPrp subunit 2 – NMR
1x5t - hPrp subunit 4 – NMR
1x5u - hPrp subunit 4 RNA-binding domain – NMR

Pre-mRNA-splicing factor 8

3sbt – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 – yeast
3e66 – yPrp β-finger domain
3e9o, 3e9p - yPrp RNA-binding domain
2p87, 2og4, 3sbg - yPrp C terminal
3lru – hPrp residues 1831-1990
3e9l – hPrp endonuclease domain
3enb - hPrp core domain IV
2p8r – Prp C terminal (mutant) – Caenorhabditis elegans

Pre-mRNA-splicing factor 9

4dgw – yPrp + Prp 21 + Prp 11

Pre-mRNA-splicing factor 18

2dk4 – hPrp splicing factor motif domain - NMR

Pre-mRNA-splicing factor 19

3lrv – yPrp WD40 domain
2bay – yPrp U-box
1n87 - yPrp U-box - NMR

Pre-mRNA-splicing factor 20

2i2y – Prp RNA-binding domain + RNA – Streptococcus – NMR
2i38 - hPrp RNA-binding domain (mutant) – NMR

snRNA-associated-splicing factor 24

2l9w – yPrp C terminal – NMR
2kh9 – yPrp residues 115-197 + RNA – NMR
2go9 – yPrp RNA-binding domains – NMR
2ghp - yPrp RNA-binding domains

Pre-mRNA-splicing factor 43P

2xau, [[3kx2 – yPrp + ADP

Pre-mRNA-splicing factor RBM22

2ytc – yPrp RNA-binding domain - NMR


Pre-mRNA-splicing factor RDS3

2k0a – yPrp - NMR

Pre-mRNA-splicing factor URN1

2juc – yPrp FF domain - NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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