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4fee
From Proteopedia
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| - | [[Image:4fee. | + | [[Image:4fee.png|left|200px]] |
{{STRUCTURE_4fee| PDB=4fee | SCENE= }} | {{STRUCTURE_4fee| PDB=4fee | SCENE= }} | ||
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===High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B=== | ===High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B=== | ||
| + | {{ABSTRACT_PUBMED_22730460}} | ||
==About this Structure== | ==About this Structure== | ||
[[4fee]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_plantarum Lactobacillus plantarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEE OCA]. | [[4fee]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_plantarum Lactobacillus plantarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEE OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022730460</ref><references group="xtra"/> | ||
[[Category: Lactobacillus plantarum]] | [[Category: Lactobacillus plantarum]] | ||
[[Category: Pyruvate oxidase]] | [[Category: Pyruvate oxidase]] | ||
Revision as of 07:29, 11 July 2012
High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B
Template:ABSTRACT PUBMED 22730460
About this Structure
4fee is a 2 chain structure with sequence from Lactobacillus plantarum. Full crystallographic information is available from OCA.
Reference
- Meyer D, Neumann P, Koers E, Sjuts H, Ludtke S, Sheldrick GM, Ficner R, Tittmann K. Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10867-72. Epub 2012 Jun 22. PMID:22730460 doi:10.1073/pnas.1201280109
Categories: Lactobacillus plantarum | Pyruvate oxidase | Ficner, R. | Koers, E. | Luedtke, S. | Meyer, D. | Neumann, P. | Sheldrick, G M. | Sjuts, H. | Tittmann, K. | Carbanion | Oxidation-reduction | Oxidoreductase | Reaction intermediate | Structure activity relationship | Thiamine diphosphate | Umpolung
