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4ags
From Proteopedia
(Difference between revisions)
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| - | [[Image:4ags. | + | [[Image:4ags.png|left|200px]] |
{{STRUCTURE_4ags| PDB=4ags | SCENE= }} | {{STRUCTURE_4ags| PDB=4ags | SCENE= }} | ||
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===Leishmania TDR1 - a unique trimeric glutathione transferase=== | ===Leishmania TDR1 - a unique trimeric glutathione transferase=== | ||
| - | {{ | + | {{ABSTRACT_PUBMED_22753509}} |
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:015056070</ref><references group="xtra"/> | + | <ref group="xtra">PMID:022753509</ref><ref group="xtra">PMID:015056070</ref><references group="xtra"/> |
[[Category: Leishmania infantum]] | [[Category: Leishmania infantum]] | ||
[[Category: Coombs, G H.]] | [[Category: Coombs, G H.]] | ||
Revision as of 07:29, 11 July 2012
Leishmania TDR1 - a unique trimeric glutathione transferase
Template:ABSTRACT PUBMED 22753509
About this Structure
4ags is a 3 chain structure with sequence from Leishmania infantum. Full crystallographic information is available from OCA.
Reference
- Fyfe PK, Westrop GD, Silva AM, Coombs GH, Hunter WN. Leishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activation. Proc Natl Acad Sci U S A. 2012 Jul 2. PMID:22753509 doi:10.1073/pnas.1202593109
- Denton H, McGregor JC, Coombs GH. Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1. Biochem J. 2004 Jul 15;381(Pt 2):405-12. PMID:15056070 doi:10.1042/BJ20040283
