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2zt5

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{{Seed}}
 
[[Image:2zt5.png|left|200px]]
[[Image:2zt5.png|left|200px]]
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{{STRUCTURE_2zt5| PDB=2zt5 | SCENE= }}
{{STRUCTURE_2zt5| PDB=2zt5 | SCENE= }}
===Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with ATP)===
===Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with ATP)===
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{{ABSTRACT_PUBMED_019710017}}
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==Disease==
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Known disease associated with this structure: Charcot-Marie-Tooth disease, type 2D OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600287 600287]], Neuropathy, distal hereditary motor, type V OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600287 600287]]
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==About this Structure==
==About this Structure==
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2ZT5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZT5 OCA].
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[[2zt5]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZT5 OCA].
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==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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==Reference==
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<ref group="xtra">PMID:019710017</ref><references group="xtra"/>
[[Category: Glycine--tRNA ligase]]
[[Category: Glycine--tRNA ligase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aminoacyl-trna synthetase]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Ap4a]]
[[Category: Ap4a]]
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[[Category: Atp]]
 
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Charcot-marie-tooth disease]]
[[Category: Charcot-marie-tooth disease]]
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[[Category: Protein biosynthesis]]
[[Category: Protein biosynthesis]]
[[Category: Trna]]
[[Category: Trna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 16:41:35 2009''
 

Revision as of 09:32, 25 July 2012

Template:STRUCTURE 2zt5

Contents

Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with ATP)

Template:ABSTRACT PUBMED 019710017

About this Structure

2zt5 is a 1 chain structure of Aminoacyl tRNA Synthetase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Guo RT, Chong YE, Guo M, Yang XL. Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis. J Biol Chem. 2009 Oct 16;284(42):28968-76. Epub 2009 Aug 26. PMID:19710017 doi:10.1074/jbc.M109.030692

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