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2uxx
From Proteopedia
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[[Image:2uxx.png|left|200px]] | [[Image:2uxx.png|left|200px]] | ||
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{{STRUCTURE_2uxx| PDB=2uxx | SCENE= }} | {{STRUCTURE_2uxx| PDB=2uxx | SCENE= }} | ||
===HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT=== | ===HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT=== | ||
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{{ABSTRACT_PUBMED_17569509}} | {{ABSTRACT_PUBMED_17569509}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2uxx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA]. | + | [[2uxx]] is a 2 chain structure of [[Lysine-specific histone demethylase 1]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA]. |
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| + | ==See Also== | ||
| + | *[[Lysine-specific histone demethylase 1|Lysine-specific histone demethylase 1]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017569509</ref><ref group="xtra">PMID:016885027</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Cole, P A.]] | [[Category: Cole, P A.]] | ||
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[[Category: Yang, M.]] | [[Category: Yang, M.]] | ||
[[Category: Yu, H.]] | [[Category: Yu, H.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Chromatin demethylation]] | [[Category: Chromatin demethylation]] | ||
[[Category: Chromatin regulator]] | [[Category: Chromatin regulator]] | ||
| - | [[Category: Coiled coil]] | ||
[[Category: Corest]] | [[Category: Corest]] | ||
[[Category: Depression]] | [[Category: Depression]] | ||
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[[Category: Nucleosome]] | [[Category: Nucleosome]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Oxidoreductase | + | [[Category: Oxidoreductase-repressor complex]] |
| - | + | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Repressor]] | [[Category: Repressor]] | ||
Revision as of 09:46, 25 July 2012
Contents |
HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT
Template:ABSTRACT PUBMED 17569509
About this Structure
2uxx is a 2 chain structure of Lysine-specific histone demethylase 1 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509 doi:10.1021/bi700664y
- Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:http://dx.doi.org/10.1016/j.molcel.2006.07.012
Categories: Homo sapiens | Cole, P A. | Culhane, J C. | Machius, M. | Yang, M. | Yu, H. | Chromatin demethylation | Chromatin regulator | Corest | Depression | Fad | Histone demethylase | Host-virus interaction | Lsd1 | Nuclear protein | Nucleosome | Oxidoreductase | Oxidoreductase-repressor complex | Phosphorylation | Repressor | Transcription | Transcription regulation | Tranylcypromine
