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1bpy

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Template:STRUCTURE 1bpy

Contents

HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA AND DDCTP

Template:ABSTRACT PUBMED 9287163

About this Structure

1bpy is a 4 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Sawaya MR, Prasad R, Wilson SH, Kraut J, Pelletier H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 1997 Sep 16;36(37):11205-15. PMID:9287163 doi:http://dx.doi.org/10.1021/bi9703812
  • Jezewska MJ, Galletto R, Bujalowski W. Rat polymerase beta binds double-stranded DNA using exclusively the 8-kDa domain. Stoichiometries, intrinsic affinities, and cooperativities. Biochemistry. 2003 May 20;42(19):5955-70. PMID:12741854 doi:10.1021/bi030046f
  • Rittenhouse RC, Apostoluk WK, Miller JH, Straatsma TP. Characterization of the active site of DNA polymerase beta by molecular dynamics and quantum chemical calculation. Proteins. 2003 Nov 15;53(3):667-82. PMID:14579358 doi:10.1002/prot.10451

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