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3gwt

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Revision as of 19:22, 25 July 2012

Image:3gwt.png

Template:STRUCTURE 3gwt

Contents

Catalytic domain of human phosphodiesterase 4B2B in complex with a quinoline inhibitor

Template:ABSTRACT PUBMED 19656678

About this Structure

3gwt is a 1 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Woodrow MD, Ballantine SP, Barker MD, Clarke BJ, Dawson J, Dean TW, Delves CJ, Evans B, Gough SL, Guntrip SB, Holman S, Holmes DS, Kranz M, Lindvaal MK, Lucas FS, Neu M, Ranshaw LE, Solanke YE, Somers DO, Ward P, Wiseman JO. Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5261-5. Epub 2009 Apr 9. PMID:19656678 doi:10.1016/j.bmcl.2009.04.012

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OCA

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