1bqo

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(New page: 200px<br /> <applet load="1bqo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bqo, resolution 2.3&Aring;" /> '''DISCOVERY OF POTENT,...)
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[[Image:1bqo.gif|left|200px]]<br /><applet load="1bqo" size="350" color="white" frame="true" align="right" spinBox="true"
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<applet load="1bqo" size="450" color="white" frame="true" align="right" spinBox="true"
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caption="1bqo, resolution 2.3&Aring;" />
caption="1bqo, resolution 2.3&Aring;" />
'''DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS'''<br />
'''DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS'''<br />
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==About this Structure==
==About this Structure==
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1BQO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with ZN, CA and N25 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BQO OCA].
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1BQO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=N25:'>N25</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BQO OCA].
==Reference==
==Reference==
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Stromelysin 1]]
[[Category: Stromelysin 1]]
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[[Category: Almstead, N.G.]]
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[[Category: Almstead, N G.]]
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[[Category: Anastasio, M.V.]]
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[[Category: Anastasio, M V.]]
[[Category: De, B.]]
[[Category: De, B.]]
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[[Category: Dunaway, C.M.]]
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[[Category: Dunaway, C M.]]
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[[Category: Dunham, K.L.M.]]
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[[Category: Dunham, K L.M.]]
[[Category: Gu, F.]]
[[Category: Gu, F.]]
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[[Category: Mcphail, S.J.]]
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[[Category: Mcphail, S J.]]
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[[Category: Mieling, G.E.]]
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[[Category: Mieling, G E.]]
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[[Category: Natchus, M.G.]]
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[[Category: Natchus, M G.]]
[[Category: Pikul, S.]]
[[Category: Pikul, S.]]
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[[Category: Rydel, T.J.]]
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[[Category: Rydel, T J.]]
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[[Category: Snider, C.E.]]
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[[Category: Snider, C E.]]
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[[Category: Taiwo, Y.O.]]
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[[Category: Taiwo, Y O.]]
[[Category: CA]]
[[Category: CA]]
[[Category: N25]]
[[Category: N25]]
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[[Category: structure-based drug design]]
[[Category: structure-based drug design]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 16:13:32 2007''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:58:04 2008''

Revision as of 09:58, 21 February 2008


1bqo, resolution 2.3Å

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DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS

Disease

Known diseases associated with this structure: Coronary heart disease, susceptibility to OMIM:[185250]

About this Structure

1BQO is a Single protein structure of sequence from Homo sapiens with , and as ligands. Active as Stromelysin 1, with EC number 3.4.24.17 Full crystallographic information is available from OCA.

Reference

Discovery of potent, achiral matrix metalloproteinase inhibitors., Pikul S, McDow Dunham KL, Almstead NG, De B, Natchus MG, Anastasio MV, McPhail SJ, Snider CE, Taiwo YO, Rydel T, Dunaway CM, Gu F, Mieling GE, J Med Chem. 1998 Sep 10;41(19):3568-71. PMID:9733482

Page seeded by OCA on Thu Feb 21 11:58:04 2008

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