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Template:STRUCTURE 2h9i
From Proteopedia
(Difference between revisions)
(New page: {{Structure |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 2h9i, resolution 2.200Å (<scene name='initialview01'>initial scene</scene>) |SITE= |LIGAND= <scene name='pdbligand=EA...) |
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{{Structure | {{Structure | ||
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 2h9i, resolution 2. | + | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2h9i]], [[Resolution|resolution]] 2.20Å (<scene name='initialview01'>default scene</scene>)}}} |
| - | + | ||
|LIGAND= <scene name='pdbligand=EAD:{(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL+[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>EAD</scene> | |LIGAND= <scene name='pdbligand=EAD:{(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL+[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>EAD</scene> | ||
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span> | ||
|GENE= inhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis]) | |GENE= inhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis]) | ||
| - | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0623 FabI], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK07889 PRK07889]</span> | ||
|RELATEDENTRY=[[1zid|1zid]] | |RELATEDENTRY=[[1zid|1zid]] | ||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h9i OCA], [http://www.ebi.ac.uk/pdbsum/2h9i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h9i RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h9i OCA], [http://www.ebi.ac.uk/pdbsum/2h9i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h9i RCSB]</span> | ||
| + | |FUNCTION={{GO|id=GO:0004318 | text = enoyl-[acyl-carrier-protein] reductase (NADH) activity}}{{GO|id=GO:0016491 | text = oxidoreductase activity}} | ||
| + | |PROCESS={{GO|id=GO:0008610 | text = lipid biosynthetic process}}{{GO|id=GO:0046677 | text = response to antibiotic}}{{GO|id=GO:0006633 | text = fatty acid biosynthetic process}}{{GO|id=GO:0008152 | text = metabolic process}} | ||
| + | |SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014358 Ipr014358], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002198 Ipr002198]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P0A5Y6 P0A5Y6]</span> | ||
| + | |uPDB=2H9I|CONSURF={{!}}- | ||
| + | {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]] | ||
| + | {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" | ||
| + | {{!}} '''Toggle Conservation Colors:''' | ||
| + | {{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}} | ||
| + | Rows = identical sequences: | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>A [x]</text> | ||
| + | <name>jmb_2h9i_A</name> | ||
| + | <title>toggle chain A</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | |||
}} | }} | ||
Current revision
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| 2h9i, resolution 2.20Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | |||||||||
| Gene: | inhA (Mycobacterium tuberculosis) | ||||||||
| Activity: | [acyl-carrier-protein_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number 1.3.1.9 | ||||||||
| Related: | 1zid | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
