Template:STRUCTURE 2h9i

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{{StructureD
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{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2h9i, resolution 2.20&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2h9i]], [[Resolution|resolution]] 2.20&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|LIGAND= <scene name='pdbligand=EAD:{(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL+[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>EAD</scene>
|LIGAND= <scene name='pdbligand=EAD:{(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL+[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>EAD</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span>
|GENE= inhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
|GENE= inhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0623 FabI], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK07889 PRK07889]</span>
 
|RELATEDENTRY=[[1zid|1zid]]
|RELATEDENTRY=[[1zid|1zid]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h9i OCA], [http://www.ebi.ac.uk/pdbsum/2h9i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h9i RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h9i OCA], [http://www.ebi.ac.uk/pdbsum/2h9i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h9i RCSB]</span>
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|PROCESS={{GO|id=GO:0008610 | text = lipid biosynthetic process}}{{GO|id=GO:0046677 | text = response to antibiotic}}{{GO|id=GO:0006633 | text = fatty acid biosynthetic process}}{{GO|id=GO:0008152 | text = metabolic process}}
|PROCESS={{GO|id=GO:0008610 | text = lipid biosynthetic process}}{{GO|id=GO:0046677 | text = response to antibiotic}}{{GO|id=GO:0006633 | text = fatty acid biosynthetic process}}{{GO|id=GO:0008152 | text = metabolic process}}
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014358 Ipr014358], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002198 Ipr002198]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P0A5Y6 P0A5Y6]</span>
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014358 Ipr014358], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002198 Ipr002198]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P0A5Y6 P0A5Y6]</span>
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|uPDB=2H9I|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
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{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
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{{!}} '''Toggle Conservation Colors:'''
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{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
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Rows = identical sequences:
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<jmol>
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<jmolButton>
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<script></script>
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<text>A [x]</text>
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<name>jmb_2h9i_A</name>
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<title>toggle chain A</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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}}
}}

Current revision

Drag the structure with the mouse to rotate
2h9i, resolution 2.20Å ()
Ligands:
Gene: inhA (Mycobacterium tuberculosis)
Activity: [acyl-carrier-protein_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number 1.3.1.9
Related: 1zid
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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