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2vkm

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[[Image:2vkm.png|left|200px]]
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{{STRUCTURE_2vkm| PDB=2vkm | SCENE= }}
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===CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)===
===CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)===
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{{ABSTRACT_PUBMED_18180160}}
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==About this Structure==
==About this Structure==
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2VKM is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKM OCA].
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[[2vkm]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKM OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation., Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1031-6. Epub 2008 Jan 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18180160 18180160]
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<ref group="xtra">PMID:018180160</ref><references group="xtra"/>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 17 13:20:52 2008''
 

Revision as of 21:15, 25 July 2012

Image:2vkm.png

Template:STRUCTURE 2vkm

Contents

CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)

Template:ABSTRACT PUBMED 18180160

About this Structure

2vkm is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J. Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1031-6. Epub 2008 Jan 3. PMID:18180160 doi:S0960-894X(07)01473-4

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OCA

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