3g0f
From Proteopedia
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Revision as of 22:51, 25 July 2012
Contents |
KIT kinase domain mutant D816H in complex with sunitinib
Template:ABSTRACT PUBMED 19164557
About this Structure
3g0f is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gajiwala KS, Wu JC, Christensen J, Deshmukh GD, Diehl W, Dinitto JP, English JM, Greig MJ, He YA, Jacques SL, Lunney EA, McTigue M, Molina D, Quenzer T, Wells PA, Yu X, Zhang Y, Zou A, Emmett MR, Marshall AG, Zhang HM, Demetri GD. KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1542-7. Epub 2009 Jan 21. PMID:19164557
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Demetri, G D. | Gajiwala, K S. | Lunney, E A. | Wu, J C. | Atp-binding | Disease mutation | Drug resistance | Glycoprotein | Immunoglobulin domain | Kinase | Kit kinase domain | Membrane | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Receptor | Sutent binding | Transferase | Transmembrane | Tyrosine-protein kinase
