This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3jsi
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3jsi.png|left|200px]] | [[Image:3jsi.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3jsi", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3jsi| PDB=3jsi | SCENE= }} | {{STRUCTURE_3jsi| PDB=3jsi | SCENE= }} | ||
===Human phosphodiesterase 9 in complex with inhibitor=== | ===Human phosphodiesterase 9 in complex with inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19919087}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19919087 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19919087}} | {{ABSTRACT_PUBMED_19919087}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3jsi]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSI OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019919087</ref><references group="xtra"/> |
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Liu, S.]] | [[Category: Liu, S.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cgmp]] | [[Category: Cgmp]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| Line 35: | Line 25: | ||
[[Category: Phosphodiesterase]] | [[Category: Phosphodiesterase]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:31:07 2009'' | ||
Revision as of 02:02, 26 July 2012
Contents |
Human phosphodiesterase 9 in complex with inhibitor
Template:ABSTRACT PUBMED 19919087
About this Structure
3jsi is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334
