3cpc
From Proteopedia
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===Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor=== | ===Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor=== | ||
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Revision as of 02:10, 26 July 2012
Contents |
Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor
Template:ABSTRACT PUBMED 18447379
About this Structure
3cpc is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hu E, Tasker A, White RD, Kunz RK, Human J, Chen N, Burli R, Hungate R, Novak P, Itano A, Zhang X, Yu V, Nguyen Y, Tudor Y, Plant M, Flynn S, Xu Y, Meagher KL, Whittington DA, Ng GY. Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. J Med Chem. 2008 Jun 12;51(11):3065-8. Epub 2008 May 1. PMID:18447379 doi:http://dx.doi.org/10.1021/jm800188g
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Gu, Y. | Long, A M. | Rose, P. | Whittington, D A. | Zhao, H. | Angiogenesis | Atp-binding | Developmental protein | Differentiation | Glycoprotein | Host-virus interaction | Immunoglobulin domain | Membrane | Nucleotide-binding | Phosphoprotein | Receptor tyrosine kinase | Transferase | Transmembrane | Tyrosine-protein kinase
