1py2
From Proteopedia
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{{STRUCTURE_1py2| PDB=1py2 | SCENE= }} | {{STRUCTURE_1py2| PDB=1py2 | SCENE= }} | ||
===Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2=== | ===Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1py2]] is a 4 chain structure of [[Interleukin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY2 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Interleukin|Interleukin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014664558</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Randal, M.]] | [[Category: Randal, M.]] | ||
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[[Category: Hot spot]] | [[Category: Hot spot]] | ||
[[Category: Il-2]] | [[Category: Il-2]] | ||
| + | [[Category: Immune system]] | ||
[[Category: Interleukin 2]] | [[Category: Interleukin 2]] | ||
[[Category: Molecular recognition]] | [[Category: Molecular recognition]] | ||
[[Category: Small molecule]] | [[Category: Small molecule]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:54:58 2009'' | ||
Revision as of 02:32, 26 July 2012
Contents |
Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2
Template:ABSTRACT PUBMED 14664558
About this Structure
1py2 is a 4 chain structure of Interleukin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Thanos CD, Randal M, Wells JA. Potent small-molecule binding to a dynamic hot spot on IL-2. J Am Chem Soc. 2003 Dec 17;125(50):15280-1. PMID:14664558 doi:10.1021/ja0382617
