1d4y
From Proteopedia
(New page: 200px<br /> <applet load="1d4y" size="450" color="white" frame="true" align="right" spinBox="true" caption="1d4y, resolution 1.97Å" /> '''HIV-1 PROTEASE TRIP...) |
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| - | [[Image:1d4y.gif|left|200px]]<br /> | + | [[Image:1d4y.gif|left|200px]]<br /><applet load="1d4y" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1d4y" size=" | + | |
caption="1d4y, resolution 1.97Å" /> | caption="1d4y, resolution 1.97Å" /> | ||
'''HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX'''<br /> | '''HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 1D4Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with TPV as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http:// | + | 1D4Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=TPV:'>TPV</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D4Y OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Janakiraman, M | + | [[Category: Janakiraman, M N.]] |
| - | [[Category: Watenpaugh, K | + | [[Category: Watenpaugh, K D.]] |
[[Category: TPV]] | [[Category: TPV]] | ||
[[Category: acid protease]] | [[Category: acid protease]] | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:13:05 2008'' |
Revision as of 10:13, 21 February 2008
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HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX
About this Structure
1D4Y is a Single protein structure of sequence from Human immunodeficiency virus 1 with as ligand. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
Reference
Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors., Thaisrivongs S, Skulnick HI, Turner SR, Strohbach JW, Tommasi RA, Johnson PD, Aristoff PA, Judge TM, Gammill RB, Morris JK, Romines KR, Chrusciel RA, Hinshaw RR, Chong KT, Tarpley WG, Poppe SM, Slade DE, Lynn JC, Horng MM, Tomich PK, Seest EP, Dolak LA, Howe WJ, Howard GM, Watenpaugh KD, et al., J Med Chem. 1996 Oct 25;39(22):4349-53. PMID:8893827
Page seeded by OCA on Thu Feb 21 12:13:05 2008
