This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3bxq
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3bxq.png|left|200px]] | [[Image:3bxq.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3bxq", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3bxq| PDB=3bxq | SCENE= }} | {{STRUCTURE_3bxq| PDB=3bxq | SCENE= }} | ||
===The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition=== | ===The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18332129}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18332129 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18332129}} | {{ABSTRACT_PUBMED_18332129}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3bxq]] is a 4 chain structure of [[Molecular Playground/Insulin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXQ OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Molecular Playground/Insulin|Molecular Playground/Insulin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018332129</ref><ref group="xtra">PMID:018492668</ref><references group="xtra"/> |
[[Category: Hu, S Q.]] | [[Category: Hu, S Q.]] | ||
[[Category: Huang, K.]] | [[Category: Huang, K.]] | ||
| Line 34: | Line 25: | ||
[[Category: Receptor binding]] | [[Category: Receptor binding]] | ||
[[Category: Tr transition]] | [[Category: Tr transition]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:51:52 2009'' | ||
Revision as of 06:01, 26 July 2012
Contents |
The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition
Template:ABSTRACT PUBMED 18332129
About this Structure
3bxq is a 4 chain structure of Molecular Playground/Insulin. Full crystallographic information is available from OCA.
See Also
Reference
- Hua QX, Nakagawa SH, Jia W, Huang K, Phillips NB, Hu SQ, Weiss MA. Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications. J Biol Chem. 2008 May 23;283(21):14703-16. Epub 2008 Mar 10. PMID:18332129 doi:10.1074/jbc.M800313200
- Wan ZL, Huang K, Hu SQ, Whittaker J, Weiss MA. The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition. J Biol Chem. 2008 Jul 25;283(30):21198-210. Epub 2008 May 20. PMID:18492668 doi:10.1074/jbc.M800235200
