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3lea

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Image:3lea.png

Template:STRUCTURE 3lea

Contents

Crystal structure of the catalytic domain of TACE with Isoindolinone-biphenyl-hydantoin inhibitor

Template:ABSTRACT PUBMED 20663669

About this Structure

3lea is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Yu W, Tong L, Kim SH, Wong MK, Chen L, Yang DY, Shankar BB, Lavey BJ, Zhou G, Kosinski A, Rizvi R, Li D, Feltz RJ, Piwinski JJ, Rosner KE, Shih NY, Siddiqui MA, Guo Z, Orth P, Shah H, Sun J, Umland S, Lundell DJ, Niu X, Kozlowski JA. Biaryl substituted hydantoin compounds as TACE inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5286-9. Epub 2010 Jul 1. PMID:20663669 doi:10.1016/j.bmcl.2010.06.134

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OCA

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