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3hfm

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Image:3hfm.png

Template:STRUCTURE 3hfm

Contents

STRUCTURE OF AN ANTIBODY-ANTIGEN COMPLEX. CRYSTAL STRUCTURE OF THE HY/HEL-10 FAB-LYSOZYME COMPLEX

Template:ABSTRACT PUBMED 2762305

About this Structure

3hfm is a 3 chain structure of Antibody and Hen Egg-White (HEW) Lysozyme with sequence from Gallus gallus and Mus musculus. The September 2001 RCSB PDB Molecule of the Month feature on Antibodies by David S. Goodsell is 10.2210/rcsb_pdb/mom_2001_9. Full crystallographic information is available from OCA.

See Also

Reference

  • Padlan EA, Silverton EW, Sheriff S, Cohen GH, Smith-Gill SJ, Davies DR. Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5938-42. PMID:2762305
  • Saul FA, Poljak RJ. Structural patterns at residue positions 9, 18, 67 and 82 in the VH framework regions of human and murine immunoglobulins. J Mol Biol. 1993 Mar 5;230(1):15-20. PMID:8450531 doi:http://dx.doi.org/10.1006/jmbi.1993.1121
  • Bridges A, Birch A, Williams G, Aguet M, Schlatter D, Huber W, Garotta G, Robinson JA. Variable region cDNA sequences and characterization of murine anti-human interferon gamma receptor monoclonal antibodies that inhibit receptor binding by interferon gamma. Mol Immunol. 1995 Dec;32(17-18):1329-38. PMID:8643102
  • Kondo H, Shiroishi M, Matsushima M, Tsumoto K, Kumagai I. Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces. J Biol Chem. 1999 Sep 24;274(39):27623-31. PMID:10488102
  • Ritchie DW, Kemp GJ. Protein docking using spherical polar Fourier correlations. Proteins. 2000 May 1;39(2):178-94. PMID:10737939

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OCA

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