2rd8
From Proteopedia
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[[Image:2rd8.png|left|200px]] | [[Image:2rd8.png|left|200px]] | ||
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{{STRUCTURE_2rd8| PDB=2rd8 | SCENE= }} | {{STRUCTURE_2rd8| PDB=2rd8 | SCENE= }} | ||
===Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195=== | ===Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195=== | ||
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{{ABSTRACT_PUBMED_18370400}} | {{ABSTRACT_PUBMED_18370400}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2rd8]] is a 2 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RD8 OCA]. | |
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+ | ==See Also== | ||
+ | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018370400</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
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[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
[[Category: Nucleotide biosynthesis]] | [[Category: Nucleotide biosynthesis]] | ||
- | + | [[Category: Transferase]] | |
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Revision as of 12:52, 26 July 2012
Contents |
Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195
Template:ABSTRACT PUBMED 18370400
About this Structure
2rd8 is a 2 chain structure of Thymidylate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gibson LM, Lovelace LL, Lebioda L. The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195. Biochemistry. 2008 Apr 22;47(16):4636-43. Epub 2008 Mar 28. PMID:18370400 doi:10.1021/bi7019386