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2qo0
From Proteopedia
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[[Image:2qo0.png|left|200px]] | [[Image:2qo0.png|left|200px]] | ||
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{{STRUCTURE_2qo0| PDB=2qo0 | SCENE= }} | {{STRUCTURE_2qo0| PDB=2qo0 | SCENE= }} | ||
===Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-(decyldithiocarbonyloxy)-undecanoic acid=== | ===Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-(decyldithiocarbonyloxy)-undecanoic acid=== | ||
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{{ABSTRACT_PUBMED_18420147}} | {{ABSTRACT_PUBMED_18420147}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2qo0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QO0 OCA]. | + | [[2qo0]] is a 2 chain structure of [[Acyl carrier protein synthase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QO0 OCA]. |
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| + | ==See Also== | ||
| + | *[[Acyl carrier protein synthase|Acyl carrier protein synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018420147</ref><ref group="xtra">PMID:011278743</ref><ref group="xtra">PMID:015713483</ref><references group="xtra"/> |
[[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | [[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
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[[Category: Wright, H T.]] | [[Category: Wright, H T.]] | ||
[[Category: Acyltransferase]] | [[Category: Acyltransferase]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Enzyme inhibitor complex]] | [[Category: Enzyme inhibitor complex]] | ||
[[Category: Fatty acid biosynthesis]] | [[Category: Fatty acid biosynthesis]] | ||
Revision as of 13:53, 26 July 2012
Contents |
Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-(decyldithiocarbonyloxy)-undecanoic acid
Template:ABSTRACT PUBMED 18420147
About this Structure
2qo0 is a 2 chain structure of Acyl carrier protein synthase with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Sachdeva S, Musayev FN, Alhamadsheh MM, Scarsdale JN, Wright HT, Reynolds KA. Separate entrance and exit portals for ligand traffic in Mycobacterium tuberculosis FabH. Chem Biol. 2008 Apr;15(4):402-12. PMID:18420147 doi:10.1016/j.chembiol.2008.03.007
- Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT. Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8. PMID:11278743 doi:10.1074/jbc.M010762200
- Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PMID:15713483 doi:10.1016/j.jmb.2004.12.044
Categories: Beta-ketoacyl-acyl-carrier-protein synthase I | Mycobacterium tuberculosis | Alhamadsheh, M. | Musayev, F. | Reynolds, K A. | Sachdeva, S. | Scarsdale, J N. | Wright, H T. | Acyltransferase | Enzyme inhibitor complex | Fatty acid biosynthesis | Lipid synthesis | Mechanism based inhibitor | Multifunctional enzyme | Myobacterium tuberculosis | Structural basis for substrate specificity | Transferase
