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2g46

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Template:STRUCTURE 2g46

Contents

structure of vSET in complex with meK27 H3 Pept. and cofactor product SAH

Template:ABSTRACT PUBMED 16603186

About this Structure

2g46 is a 4 chain structure of Histone methyltransferase with sequence from Paramecium bursaria chlorella virus 1. Full experimental information is available from OCA.

See Also

Reference

  • Qian C, Wang X, Manzur K, Sachchidanand, Farooq A, Zeng L, Wang R, Zhou MM. Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase. J Mol Biol. 2006 May 26;359(1):86-96. Epub 2006 Mar 20. PMID:16603186 doi:10.1016/j.jmb.2006.03.006
  • Zhang X, Bruice TC. A quantum mechanics/molecular mechanics study of the catalytic mechanism and product specificity of viral histone lysine methyltransferase. Biochemistry. 2007 Aug 28;46(34):9743-51. Epub 2007 Aug 3. PMID:17676763 doi:10.1021/bi700515q

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