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3hnb
From Proteopedia
(Difference between revisions)
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[[Image:3hnb.png|left|200px]] | [[Image:3hnb.png|left|200px]] | ||
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===Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor=== | ===Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor=== | ||
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{{ABSTRACT_PUBMED_20089867}} | {{ABSTRACT_PUBMED_20089867}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hemophilia A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=306700 306700]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3hnb]] is a 1 chain structure of [[Factor VIII]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNB OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor VIII|Factor VIII]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020089867</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Liu, Z.]] | [[Category: Liu, Z.]] | ||
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[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
[[Category: Small molecule inhibitor/blood clotting]] | [[Category: Small molecule inhibitor/blood clotting]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:59:07 2010'' | ||
Revision as of 14:48, 26 July 2012
Contents |
Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Template:ABSTRACT PUBMED 20089867
About this Structure
3hnb is a 1 chain structure of Factor VIII with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. J Biol Chem. 2010 Mar 19;285(12):8824-9. Epub 2010 Jan 20. PMID:20089867 doi:10.1074/jbc.M109.080168
