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1e3q
From Proteopedia
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[[Image:1e3q.png|left|200px]] | [[Image:1e3q.png|left|200px]] | ||
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{{STRUCTURE_1e3q| PDB=1e3q | SCENE= }} | {{STRUCTURE_1e3q| PDB=1e3q | SCENE= }} | ||
===TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH BW284C51=== | ===TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH BW284C51=== | ||
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*[[AChE bivalent inhibitors (Part II)|AChE bivalent inhibitors (Part II)]] | *[[AChE bivalent inhibitors (Part II)|AChE bivalent inhibitors (Part II)]] | ||
*[[Acetylcholinesterase|Acetylcholinesterase]] | *[[Acetylcholinesterase|Acetylcholinesterase]] | ||
| - | *[[Alzheimer's Disease|Alzheimer's Disease]] | ||
==Reference== | ==Reference== | ||
Revision as of 17:34, 26 July 2012
Contents |
TORPEDO CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH BW284C51
Template:ABSTRACT PUBMED 12351819
About this Structure
1e3q is a 1 chain structure of Acetylcholinesterase with sequence from Torpedo californica. Full crystallographic information is available from OCA.
See Also
Reference
- Felder CE, Harel M, Silman I, Sussman JL. Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase. Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 2):1765-71. Epub, 2002 Sep 28. PMID:12351819
- Kryger G, Silman I, Sussman JL. Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs. Structure. 1999 Mar 15;7(3):297-307. PMID:10368299
- Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9031-5. PMID:8415649
- Bourne Y, Taylor P, Radic Z, Marchot P. Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site. EMBO J. 2003 Jan 2;22(1):1-12. PMID:12505979 doi:http://dx.doi.org/10.1093/emboj/cdg005
