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2g1q

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Revision as of 19:39, 26 July 2012

Image:2g1q.png

Template:STRUCTURE 2g1q

Contents

crystal structure of KSP in complex with inhibitor 9h

Template:ABSTRACT PUBMED 16603356

About this Structure

2g1q is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Cox CD, Torrent M, Breslin MJ, Mariano BJ, Whitman DB, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Schaber MD, Lobell RB, Tao W, South VJ, Kohl NE, Yan Y, Kuo LC, Prueksaritanont T, Slaughter DE, Li C, Mahan E, Lu B, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3175-9. Epub 2006 Apr 5. PMID:16603356 doi:10.1016/j.bmcl.2006.03.040

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OCA

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