2o2f

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[[Image:2o2f.png|left|200px]]
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{{STRUCTURE_2o2f| PDB=2o2f | SCENE= }}
{{STRUCTURE_2o2f| PDB=2o2f | SCENE= }}
===Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand===
===Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand===
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{{ABSTRACT_PUBMED_17256834}}
{{ABSTRACT_PUBMED_17256834}}
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==Disease==
 
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Known disease associated with this structure: Leukemia/lymphoma, B-cell OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151430 151430]]
 
==About this Structure==
==About this Structure==
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2O2F is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2F OCA].
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[[2o2f]] is a 1 chain structure of [[Bcl-2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2F OCA].
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==See Also==
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*[[Bcl-2|Bcl-2]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17256834</ref><references group="xtra"/>
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<ref group="xtra">PMID:017256834</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Belli, B A.]]
[[Category: Belli, B A.]]
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[[Category: Bcl]]
[[Category: Bcl]]
[[Category: Complex]]
[[Category: Complex]]
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[[Category: Nmr]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:56:44 2009''
 

Revision as of 20:40, 26 July 2012

Image:2o2f.png

Template:STRUCTURE 2o2f

Contents

Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand

Template:ABSTRACT PUBMED 17256834

About this Structure

2o2f is a 1 chain structure of Bcl-2 with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  • Bruncko M, Oost TK, Belli BA, Ding H, Joseph MK, Kunzer A, Martineau D, McClellan WJ, Mitten M, Ng SC, Nimmer PM, Oltersdorf T, Park CM, Petros AM, Shoemaker AR, Song X, Wang X, Wendt MD, Zhang H, Fesik SW, Rosenberg SH, Elmore SW. Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL. J Med Chem. 2007 Feb 22;50(4):641-62. Epub 2007 Jan 26. PMID:17256834 doi:http://dx.doi.org/10.1021/jm061152t

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