3gis

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[[Image:3gis.png|left|200px]]
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{{STRUCTURE_3gis| PDB=3gis | SCENE= }}
{{STRUCTURE_3gis| PDB=3gis | SCENE= }}
===Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin===
===Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin===
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{{ABSTRACT_PUBMED_19656282}}
{{ABSTRACT_PUBMED_19656282}}
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==Disease==
 
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Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
 
==About this Structure==
==About this Structure==
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3GIS is a 9 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIS OCA].
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[[3gis]] is a 9 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIS OCA].
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==See Also==
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*[[Thrombin|Thrombin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19656282</ref><references group="xtra"/>
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<ref group="xtra">PMID:019656282</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
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[[Category: Calcium]]
 
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Coagulation]]
[[Category: Coagulation]]
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[[Category: Kringle]]
[[Category: Kringle]]
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[[Category: Pharmaceutical]]
 
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[[Category: Polymorphism]]
 
[[Category: Protease]]
[[Category: Protease]]
[[Category: Protein-protein complex]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:29:01 2009''
 

Revision as of 22:02, 26 July 2012

Template:STRUCTURE 3gis

Contents

Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin

Template:ABSTRACT PUBMED 19656282

About this Structure

3gis is a 9 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Adams TE, Li W, Huntington JA. Molecular basis of thrombomodulin activation of slow thrombin. J Thromb Haemost. 2009 Oct;7(10):1688-95. Epub 2009 Jul 28. PMID:19656282 doi:10.1111/j.1538-7836.2009.03563.x

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