3h1v
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | [[Image:3h1v.png|left|200px]] | |
| - | [[Image:3h1v. | + | |
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3h1v", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3h1v| PDB=3h1v | SCENE= }} | {{STRUCTURE_3h1v| PDB=3h1v | SCENE= }} | ||
===Human glucokinase in complex with a synthetic activator=== | ===Human glucokinase in complex with a synthetic activator=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19736020}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19736020 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19736020}} | {{ABSTRACT_PUBMED_19736020}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Diabetes mellitus, gestational OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138079 138079]], Diabetes mellitus, noninsulin-dependent, late onset OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138079 138079]], Diabetes mellitus, permanent neonatal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138079 138079]], Hyperinsulinemic hypoglycemia, familial, 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138079 138079]], MODY, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138079 138079]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3h1v]] is a 1 chain structure of [[Hexokinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H1V OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Hexokinase|Hexokinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019736020</ref><references group="xtra"/> |
[[Category: Glucokinase]] | [[Category: Glucokinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 32: | Line 20: | ||
[[Category: Takahashi, K.]] | [[Category: Takahashi, K.]] | ||
[[Category: Allosteric activator]] | [[Category: Allosteric activator]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Diabetes]] | [[Category: Diabetes]] | ||
| Line 41: | Line 28: | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 14:04:44 2009'' | ||
Revision as of 00:26, 27 July 2012
Contents |
Human glucokinase in complex with a synthetic activator
Template:ABSTRACT PUBMED 19736020
About this Structure
3h1v is a 1 chain structure of Hexokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Takahashi K, Hashimoto N, Nakama C, Kamata K, Sasaki K, Yoshimoto R, Ohyama S, Hosaka H, Maruki H, Nagata Y, Eiki J, Nishimura T. The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators. Bioorg Med Chem. 2009 Oct 1;17(19):7042-51. Epub 2009 May 21. PMID:19736020 doi:10.1016/j.bmc.2009.05.037
