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3bft

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[[Image:3bft.png|left|200px]]
[[Image:3bft.png|left|200px]]
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{{STRUCTURE_3bft| PDB=3bft | SCENE= }}
{{STRUCTURE_3bft| PDB=3bft | SCENE= }}
===Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution===
===Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution===
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{{ABSTRACT_PUBMED_18269227}}
{{ABSTRACT_PUBMED_18269227}}
==About this Structure==
==About this Structure==
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[[3bft]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFT OCA].
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[[3bft]] is a 3 chain structure of [[Ionotropic Glutamate Receptors]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFT OCA].
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==See Also==
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*[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18269227</ref><ref group="xtra">PMID:11086992</ref><references group="xtra"/>
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<ref group="xtra">PMID:018269227</ref><ref group="xtra">PMID:011086992</ref><references group="xtra"/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Beich-Frandsen, M.]]
[[Category: Beich-Frandsen, M.]]
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[[Category: Vestergaard, B.]]
[[Category: Vestergaard, B.]]
[[Category: Agonist]]
[[Category: Agonist]]
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[[Category: Alternative splicing]]
 
[[Category: Ampa receptor]]
[[Category: Ampa receptor]]
[[Category: Cell junction]]
[[Category: Cell junction]]

Revision as of 01:54, 27 July 2012

Image:3bft.png

Template:STRUCTURE 3bft

Contents

Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution

Template:ABSTRACT PUBMED 18269227

About this Structure

3bft is a 3 chain structure of Ionotropic Glutamate Receptors with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  • Beich-Frandsen M, Pickering DS, Mirza O, Johansen TN, Greenwood J, Vestergaard B, Schousboe A, Gajhede M, Liljefors T, Kastrup JS. Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J Med Chem. 2008 Mar 13;51(5):1459-63. Epub 2008 Feb 13. PMID:18269227 doi:10.1021/jm701126w
  • Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992

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