3ixk

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Revision as of 02:53, 27 July 2012

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Template:STRUCTURE 3ixk

Contents 1 Potent beta-secretase 1 inhibitor 2 About this Structure 3 See Also 4 Reference

Potent beta-secretase 1 inhibitor

Template:ABSTRACT PUBMED 20036448

About this Structure

3ixk is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Wangsell F, Gustafsson K, Kvarnstrom I, Borkakoti N, Edlund M, Jansson K, Lindberg J, Hallberg A, Rosenquist A, Samuelsson B. Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core. Eur J Med Chem. 2010 Mar;45(3):870-82. Epub 2009 Nov 12. PMID:20036448 doi:10.1016/j.ejmech.2009.11.013