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2yir
From Proteopedia
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[[Image:2yir.png|left|200px]] | [[Image:2yir.png|left|200px]] | ||
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{{STRUCTURE_2yir| PDB=2yir | SCENE= }} | {{STRUCTURE_2yir| PDB=2yir | SCENE= }} | ||
===STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1352=== | ===STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1352=== | ||
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==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
Revision as of 05:07, 27 July 2012
Contents |
STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1352
Template:ABSTRACT PUBMED 21907711
About this Structure
2yir is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lountos GT, Jobson AG, Tropea JE, Self CR, Zhang G, Pommier Y, Shoemaker RH, Waugh DS. X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket. FEBS Lett. 2011 Oct 20;585(20):3245-9. Epub 2011 Sep 7. PMID:21907711 doi:10.1016/j.febslet.2011.08.050
- Lountos GT, Tropea JE, Zhang D, Jobson AG, Pommier Y, Shoemaker RH, Waugh DS. Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor. Protein Sci. 2009 Jan;18(1):92-100. PMID:19177354 doi:10.1002/pro.16
