2f3f
From Proteopedia
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===Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor=== | ===Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2f3f]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3F OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016854060</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Aspartic protease]] | [[Category: Aspartic protease]] | ||
[[Category: Beta-secretase]] | [[Category: Beta-secretase]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Macrocyclic peptidomimetic inhibitor]] | [[Category: Macrocyclic peptidomimetic inhibitor]] | ||
[[Category: Memapsin2]] | [[Category: Memapsin2]] | ||
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Revision as of 07:26, 27 July 2012
Contents |
Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor
Template:ABSTRACT PUBMED 16854060
About this Structure
2f3f is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M. Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:16854060 doi:10.1021/jm060154a
