3jz2

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[[Image:3jz2.png|left|200px]]
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{{STRUCTURE_3jz2| PDB=3jz2 | SCENE= }}
{{STRUCTURE_3jz2| PDB=3jz2 | SCENE= }}
===Crystal structure of human thrombin mutant N143P in E* form===
===Crystal structure of human thrombin mutant N143P in E* form===
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{{ABSTRACT_PUBMED_19846563}}
{{ABSTRACT_PUBMED_19846563}}
==About this Structure==
==About this Structure==
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[[3jz2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ2 OCA].
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[[3jz2]] is a 2 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ2 OCA].
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==See Also==
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*[[Thrombin|Thrombin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19846563</ref><ref group="xtra">PMID:18250335</ref><ref group="xtra">PMID:15152000</ref><references group="xtra"/>
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<ref group="xtra">PMID:019846563</ref><ref group="xtra">PMID:018250335</ref><ref group="xtra">PMID:015152000</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
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[[Category: Calcium]]
 
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Kringle]]
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[[Category: Pharmaceutical]]
 
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[[Category: Polymorphism]]
 
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 11:49, 27 July 2012

Image:3jz2.png

Template:STRUCTURE 3jz2

Contents

Crystal structure of human thrombin mutant N143P in E* form

Template:ABSTRACT PUBMED 19846563

About this Structure

3jz2 is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Niu W, Chen Z, Bush-Pelc LA, Bah A, Gandhi PS, Di Cera E. Mutant N143P reveals how Na+ activates thrombin. J Biol Chem. 2009 Dec 25;284(52):36175-85. Epub 2009 Oct 21. PMID:19846563 doi:10.1074/jbc.M109.069500
  • Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
  • Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200

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