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3nnx

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Revision as of 12:47, 27 July 2012

Image:3nnx.png

Template:STRUCTURE 3nnx

Contents

Crystal structure of phosphorylated P38 alpha in complex with DP802

Template:ABSTRACT PUBMED 20800479

About this Structure

3nnx is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Ahn YM, Clare M, Ensinger CL, Hood MM, Lord JW, Lu WP, Miller DF, Patt WC, Smith BD, Vogeti L, Kaufman MD, Petillo PA, Wise SC, Abendroth J, Chun L, Clark R, Feese M, Kim H, Stewart L, Flynn DL. Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5793-8. Epub 2010 Aug 3. PMID:20800479 doi:10.1016/j.bmcl.2010.07.134

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OCA

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