This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2k2g
From Proteopedia
m (Protected "2k2g" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:2k2g.png|left|200px]] | [[Image:2k2g.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2k2g", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2k2g| PDB=2k2g | SCENE= }} | {{STRUCTURE_2k2g| PDB=2k2g | SCENE= }} | ||
| Line 13: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2k2g]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2G OCA]. | + | [[2k2g]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2G OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Elastase]] | + | *[[Elastase|Elastase]] |
| + | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018425585</ref><ref group="xtra">PMID:015803400</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
| Line 30: | Line 25: | ||
[[Category: Wilhelm, J.]] | [[Category: Wilhelm, J.]] | ||
[[Category: Wolfrom, S.]] | [[Category: Wolfrom, S.]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Catalytic domain]] | [[Category: Catalytic domain]] | ||
[[Category: Extracellular matrix]] | [[Category: Extracellular matrix]] | ||
| Line 40: | Line 34: | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protein-ligand structure]] | [[Category: Protein-ligand structure]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 13:21, 27 July 2012
Contents |
Solution structure of the wild-type catalytic domain of human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor
About this Structure
2k2g is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full experimental information is available from OCA.
See Also
Reference
- Markus MA, Dwyer B, Wolfrom S, Li J, Li W, Malakian K, Wilhelm J, Tsao DH. Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor. J Biomol NMR. 2008 May;41(1):55-60. Epub 2008 Apr 19. PMID:18425585 doi:10.1007/s10858-008-9236-4
- Markus MA, Dwyer B, Wolfrom S, Li J, Li W, Malakian K, Wilhelm J, Tsao DH. 1H, 13C, and 15N assignments of MMP-12, a key protease implicated in lung tissue remodeling. J Biomol NMR. 2005 Mar;31(3):260. PMID:15803400 doi:10.1007/s10858-005-0181-1
Categories: Homo sapiens | Macrophage elastase | Dwyer, B. | Li, J. | Li, W. | Malakian, K. | Markus, M A. | Tsao, D H.H. | Wilhelm, J. | Wolfrom, S. | Catalytic domain | Extracellular matrix | Glycoprotein | Human gene | Hydrolase | Matrix metalloproteinase | Metal-binding | Metalloprotease | Protease | Protein-ligand structure | Secreted | Zymogen
