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2qdj

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[[Image:2qdj.png|left|200px]]
[[Image:2qdj.png|left|200px]]
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{{STRUCTURE_2qdj| PDB=2qdj | SCENE= }}
{{STRUCTURE_2qdj| PDB=2qdj | SCENE= }}
===Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture===
===Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture===
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{{ABSTRACT_PUBMED_17996702}}
{{ABSTRACT_PUBMED_17996702}}
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==Disease==
 
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Known disease associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Pinealoma with bilateral retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]]
 
==About this Structure==
==About this Structure==
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2QDJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDJ OCA].
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[[2qdj]] is a 1 chain structure of [[Retinoblastoma protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDJ OCA].
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==See Also==
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*[[Retinoblastoma protein|Retinoblastoma protein]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17996702</ref><references group="xtra"/>
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<ref group="xtra">PMID:017996702</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hassler, M.]]
[[Category: Hassler, M.]]
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[[Category: Cyclin fold]]
[[Category: Cyclin fold]]
[[Category: Cyclin wedge]]
[[Category: Cyclin wedge]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:15:35 2009''
 

Revision as of 13:47, 27 July 2012

Template:STRUCTURE 2qdj

Contents

Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture

Template:ABSTRACT PUBMED 17996702

About this Structure

2qdj is a 1 chain structure of Retinoblastoma protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Hassler M, Singh S, Yue WW, Luczynski M, Lakbir R, Sanchez-Sanchez F, Bader T, Pearl LH, Mittnacht S. Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol Cell. 2007 Nov 9;28(3):371-85. PMID:17996702 doi:10.1016/j.molcel.2007.08.023

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