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3bel
From Proteopedia
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[[Image:3bel.png|left|200px]] | [[Image:3bel.png|left|200px]] | ||
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{{STRUCTURE_3bel| PDB=3bel | SCENE= }} | {{STRUCTURE_3bel| PDB=3bel | SCENE= }} | ||
===X-ray structure of EGFR in complex with oxime inhibitor=== | ===X-ray structure of EGFR in complex with oxime inhibitor=== | ||
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{{ABSTRACT_PUBMED_18508264}} | {{ABSTRACT_PUBMED_18508264}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Epidermal Growth Factor Receptor]] | + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018508264</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Struble, G T.]] | [[Category: Struble, G T.]] | ||
[[Category: Xu, G.]] | [[Category: Xu, G.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Anti-oncogene]] | [[Category: Anti-oncogene]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | [[Category: Ubl conjugation]] | ||
Revision as of 15:21, 27 July 2012
Contents |
X-ray structure of EGFR in complex with oxime inhibitor
Template:ABSTRACT PUBMED 18508264
About this Structure
3bel is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Xu G, Searle LL, Hughes TV, Beck AK, Connolly PJ, Abad MC, Neeper MP, Struble GT, Springer BA, Emanuel SL, Gruninger RH, Pandey N, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Greenberger LM. Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3495-9. Epub 2008 May 10. PMID:18508264 doi:http://dx.doi.org/10.1016/j.bmcl.2008.05.024
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Abad, M C. | Connolly, P J. | Gaul, M D. | Neeper, M P. | Struble, G T. | Xu, G. | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Glycoprotein | Kinase domain | Membrane | Nucleotide-binding | Phosphoprotein | Receptor | Secreted | Transferase | Transmembrane | Tyrosine-protein kinase
