4f1s

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'''Unreleased structure'''
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[[Image:4f1s.jpg|left|200px]]
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The entry 4f1s is ON HOLD until Paper Publication
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{{STRUCTURE_4f1s| PDB=4f1s | SCENE= }}
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Authors: Whittington, D.A., Tang, J., Yakowec, P.
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===Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor===
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Description: Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor
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{{ABSTRACT_PUBMED_22832322}}
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==About this Structure==
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[[4f1s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F1S OCA].
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==Reference==
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<ref group="xtra">PMID:022832322</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Tang, J.]]
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[[Category: Whittington, D A.]]
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[[Category: Yakowec, P.]]
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[[Category: Lipid kinase]]
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[[Category: P85]]
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[[Category: Phosphotransferase]]
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[[Category: Transferase-inhibitor complex]]

Revision as of 05:15, 8 August 2012

Template:STRUCTURE 4f1s

Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor

Template:ABSTRACT PUBMED 22832322

About this Structure

4f1s is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wurz RP, Liu L, Yang K, Nishimura N, Bo Y, Pettus LH, Caenepeel S, Freeman DJ, McCarter JD, Mullady EL, Miguel TS, Wang L, Zhang N, Andrews KL, Whittington DA, Jiang J, Subramanian R, Hughes PE, Norman MH. Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold. Bioorg Med Chem Lett. 2012 Jul 3. PMID:22832322 doi:10.1016/j.bmcl.2012.06.078

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